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San Antonio (/ˌsæn ænˈtoʊnioʊ/ SAN an-TOH-nee-oh; Spanish for "Saint Anthony"), officially the City of San Antonio, is the seventh-most populous city in the United States, second largest city in the Southern United States, and the second-most populous city in Texas as well as the 12th most populous city in North America with 1,434,625 residents in 2020. Founded as a Spanish mission and colonial outpost in 1718, the city became the first chartered civil settlement in present-day Texas in 1731. The area was still part of the Spanish Empire, and later of the Mexican Republic. It is the state's oldest municipality, having celebrated its 300th anniversary on May 1, 2018.